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Zesty Pepperoncini Slow Cooker Italian Beef

07/07/2025 by Nathaniel Lee

If you’re craving a hearty, comforting meal that brings a taste of Italy right to your kitchen, look no further than this Zesty Pepperoncini Slow Cooker Italian Beef. With succulent beef roast, tangy peppers, and fragrant herbs, it comes together easily in a slow cooker for a deliciously hassle-free supper.

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Ingredients

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  • 3–4 pounds beef chuck roast
  • 1 cup beef broth
  • 1 (16-ounce) jar pepperoncini, with liquid
  • 1 tablespoon dried oregano
  • 2 teaspoons dried basil
  • 1 teaspoon garlic powder
  • 1 teaspoon onion powder
  • Salt and black pepper, to taste
  • Toasted Italian rolls (optional, for serving)

Instructions

Begin by patting your chuck roast dry and seasoning it generously with salt and black pepper on all sides. Warm a skillet over medium-high heat with a drizzle of oil, then sear the roast for a minute or two on each side to lock in flavor. Transfer the roast to your slow cooker.

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Next, pour in the beef broth, then add the entire jar of pepperoncini with its liquid. Sprinkle the dried oregano, basil, garlic powder, and onion powder evenly around the roast. Cover and cook on low for about 8 hours (or on high for about 4–5 hours), until the beef is fork-tender.

Once the beef is fully cooked, shred it directly in the slow cooker with two forks, allowing the meat to soak up the flavorful cooking liquid. Pile the shredded beef onto toasted Italian rolls for sandwiches, or enjoy it alongside roasted vegetables for a low-carb option.

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This savory slow cooker Italian beef is a winner for busy weeknights, game days, or any time you want a hearty and effortless meal. The tang from the pepperoncini gives it a unique zing, while the slow cooking leaves the meat melt-in-your-mouth tender.

You can swap out the pepperoncini for banana peppers if you prefer a milder kick, or add more garlic for a bolder taste. Whether you’re a beef lover or simply enjoy a classic Italian-inspired dish, this recipe is sure to become a family favorite.

Nathaniel Lee
Nathaniel Lee

Nathaniel Lee is an avid cook, drawing on his decades of home cooking and fine dining experience. He is a contributing chef at Mashed, and his recipes and contributions have been featured in Tasting Table, Edible Arrangements, Insanely Good Recipes, and The Daily Meal.

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