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Bold Pepperoncini Slow Cooker Italian Beef Sandwiches

03/19/2025 by Nathaniel Lee

If you’re looking for a mouthwatering meal that requires minimal effort but packs a hearty punch, these Bold Pepperoncini Slow Cooker Italian Beef Sandwiches will become your new go-to. Juicy, tender beef infused with tangy peppers and aromatic herbs—just the thing for a cozy weeknight dinner or a casual get-together with friends.

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Ingredients

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  • 3 pounds boneless beef chuck roast
  • 1 teaspoon salt
  • ½ teaspoon freshly ground black pepper
  • 1 teaspoon dried oregano
  • 1 teaspoon dried basil
  • 1 cup beef broth
  • ½ cup sliced pepperoncini peppers, plus a splash of their brine
  • 1 onion, thinly sliced
  • 4 to 6 crusty rolls
  • Provolone slices (optional, for topping)

Instructions

Start by seasoning the chuck roast generously with salt, pepper, oregano, and basil. In a slow cooker, arrange the sliced onion as a bed at the bottom. Place the roast on top of the onion, then pour in the beef broth, pepperoncini peppers, and a little of their spicy brine for an extra zing.

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Cover and cook on low for about 8 hours (or on high for about 4 to 5 hours), until the beef is fork-tender. Once done, shred the beef directly in the slow cooker, letting it soak up all the tantalizing juices. Toast the rolls lightly, then load them up with generous heaps of shredded beef, onions, and peppers. If you like a cheesy finish, top each sandwich with provolone slices and let them melt into the savory goodness.

These bold, comforting sandwiches are perfect for busy families, game-day gatherings, or anyone craving a hearty meal without too much fuss. If you want a leaner option, try using a bottom round roast or substitute turkey breast. For those avoiding gluten, swap in your favorite gluten-free rolls or serve the beef over a bowl of steamed vegetables. However you enjoy it, the peppery tang and deep, slow-cooked flavors will have everyone coming back for seconds.

Nathaniel Lee
Nathaniel Lee

Nathaniel Lee is an avid cook, drawing on his decades of home cooking and fine dining experience. He is a contributing chef at Mashed, and his recipes and contributions have been featured in Tasting Table, Edible Arrangements, Insanely Good Recipes, and The Daily Meal.

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